The Biogenesis, dynamic and homeostasis of membrane lipids (Lipid) team has a solid knowledge in the field of plant glycerolipids. The work is in line with the past research of the team, i.e. advancing knowledge of the processes setting up the membrane lipid distribution in plastid-containing eukaryotes at steady state (membrane lipid homeostasis) and tuning this steady state in response to environmental changes (lipid remodeling). The overall strategy remains to consider the glycerolipid metabolic scheme as a system, and to contribute to the international effort to characterize its components and dynamics by a multidisciplinary approach.
The team is affiliated to:
- Institut Carnot 3BCAR (Bioénergies, Biomolécules et Biomatériaux du CArbone Renouvelable);
- IMBL (Institut Multidisciplinaire de Biochimie des Lipides);
- GERLI (Groupe d'Etude et de Recherche en Lipidomique);
- Lipidomystes;
- LABEX GRAL;
- OCEANOMICS consortium (Biotechnologie et bioressources pour la valorisation des écosystèmes marins planctoniques).
Research thema
Our aims are to:- characterize lipid trafficking and flow between organelles;
- decipher the role and control of lipid homeostasis at the membrane, cell and organism levels;
- reconstruct the pathways of membrane lipid synthesis;
- establish the relationships among lipid biosynthesis, membrane expansion and cell architecture;
- understand the link with the abiotic environment of the organisms, in particular the oligotrophic environments poor in nutrients, and the thermal variations, cold, snow, ice.
Funded projects supported by:
The National Agency for Research / ANR:
ANR JCJC ChloroMitoLipid, coord. J. Jouhet
ANR RéGal, coord. E. Maréchal, coll. A. Girard-Egrot, Lyon & C. Breton, Grenoble
ANR DiaDomOil, coord. E. Maréchal, coll. C. Bowler & A. Falciatore, Paris & Fermentalg, Libourne
ANR Reglisse, coord. L. Nussaume, coll. L. Nussaume, Cadarache
ANR BLinK, coord. J. Jouhet, coll. B. Demé, Grenoble & E. Schneck, Potsdam (Germany)
Institut Carnot 3BCAR (coll. E. Maréchal & S. Baud, Versailles)
CEA DRF Impulsion (coll. D. Falconet & PH Jouneau IRIG/MEM; coll. E. Maréchal & M. Gromova, IRIG/MEM; coll. J. Jouhet, J. Bourguignon, PCV/MetalStress, C. Raillon, IRIG/SYMMES & Romain Vives IRIG/IBS)
Inra with the Oleum project (J. Salvaing)
Univ. Grenoble-Alpes with the Cross Disciplinary Projects Glyco@Alps (member of the scientific committee: E. Maréchal) &
Origin of Life (member of the scientific committee: O. Bastien & D. Falconet).
Industrial partnerships
 • the
Fermentalg company. Read the March 3, 2014
Press release entitled:
Fermentalg and the CEA optimize the production of microalgae in a mixotrophic environment. |
|
|
|
|