Team leaders

Jacques Bourguignon Phone: 04 38 78 46 88

Stéphane Ravanel Phone: 04 38 78 33 83

Address
Laboratoire Physiologie Cellulaire & Végétale
CEA-Grenoble
17 avenue des Martyrs
38 054 Grenoble cedex 9
France

Members of the team


ALBAN Claude, INRAE Researcher Director, Claude.Alban[@]cea.fr
BEAULIER Camille, PhD Student, Camille.Beaulier[@]cea.fr
BOURGUIGNON Jacques, CEA Research Director, MetalStress, Jacques.Bourguignon[@]cea.fr
DEVIME Fabienne, INRAE Engineer Assistant, Fabienne.Devime[@]cea.fr
FIGUET Sylvie, INRAE Technician, Sylvie.Figuet[@]cea.fr
GALEONE Adrien, INRAE Assistant Engineer, Adrien.Galeone2[@]cea.fr
MARTIN-LAFFON Jacqueline, CNRS Research Engineer, Jacqueline.Martin-Laffon[@]cea.fr
PRZYBYLA-TOSCANO Jonathan, INRAE Researcher, Jonathan.Przybyla-Toscano[@]cea.fr
RAILLON Camille, CEA Researcher, MétalStress Team, Camille.Raillon[@]cea.fr
RAVANEL Stéphane, INRAE Research Director, Stephane.Ravanel[@]cea.fr

Presentation
Contamination of soil and water by heavy metals (HM) represents a major environmental hazard to human health. Soil pollution by HM currently affects about 235 million hectares. Understanding how plants respond to HM is crucial in the quest to improve plant capacity to resist to HM pollution. Inside the plant, different processes contribute to enhance metal tolerance; including extracellular immobilization (cell wall and other carbohydrates), active exclusion into the apoplast, chelation in the cytosol and sequestration into the vacuoles.

Therefore, a better comprehension of the molecular mechanisms controlling these processes, as well as understanding metal toxicity and accumulation in plants, is of prime importance to design new strategies of phytoremediation via engineered plants or natural hyperaccumulators but also for phytomining and food crop biofortification. This is also very important for the selection of crops with low HM contents, or from an ecotoxicological point of view, for example to identify biomarkers of pollution.

We are interested in evaluating the impact of HM stresses on cell function and elucidating the biochemical and physiological defense mechanisms adopted by plants to counter these stresses.

Keywords
Heavy metal stress, heavy metal detoxification, cadmium, cesium, RMN, ICP-MS, proteomics, metabolomics, transcriptomics, vacuole, selenium binding protein, Arabidopsis, plant cells and algae cultures, uranium, phytoremediation, MeP pathway, light stress, phosphate deficiency)