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Actin: An under control actor of cellular architecture

Relying on the original use of biomimetic tools, researchers from our laboratory [1] experimentally observed the assembly modalities of actin filaments networks and determined by computational modeling and the mechanical and probabilistic laws governing the formation of these networks.

Published on 19 September 2010
These results are published online in Nature Materials
Press release available in French.

Actin filaments, polymerizing from a circle-shaped micropattern (left-hand image) or star (right-hand image), interact to give complex networks of very different structures. The image on the right is a superposition of 30 identical micropatterns showing the reproducibility of these networks.

[1] Collaboration:
- Institut de Recherches en Technologies et Sciences pour le Vivant, iRTSV, Laboratoire de Physiologie Cellulaire et Végétale, CNRS/CEA/INRA/UJF, Grenoble
- Laboratoire Techniques de l'Ingénierie Médicale et de la Complexité, CNRS/UJF, Pavillon Taillefer Faculté de Médecine, La Tronche.

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