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Maintaining the architectural integrity of a cell, its deformation, motility, are provided by the cytoskeleton in which a predominant component is an organic polymer: the actin filament. Knowledge of the molecular mechanisms of the dynamic assembly of these polymers will be useful in the fight against certain diseases found in embryology, oncology or in neurodegenerative diseases.
To access the information at the molecular level, we use a novel imaging technique (the evanescent wave microscopy) that allows the study of actin dynamics at the molecular level and track real time individual actin filaments within orderly actin structures.
Highlight available in French.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.