Copper pathway in the chloroplast

Researchers at the Cell & Plant Physiology Laboratory and at the Chemistry and Biology of Metals laboratory from our institute study the copper homeostasis in plants. They propose a model of copper path within the membrane domains of HMA6 and HMA8 chloroplastic carriers.

Published on 28 November 2016

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Copper transport model at the membrane domain of ATPase-Cu⁺ HMA6.

The cysteine and histidine residues of the L1 loop identified and characterized biochemically in this study are stained in red. They are necessary for the release of the metal.

^[1] Catty et al. Journal of Biological Chemistry, 2011

^[2] Sautron et al. Bioscience Report, 2015

^[3] Mayerhofer H, Sautron E, Rolland N, Catty P, Seigneurin-Berny D, Pebay-Peyroula E and Ravaud S. Structural insights into the Nucleotide-Binding Domains of the P_1B-type ATPases HMA6 and HMA8 from Arabidopsis thaliana. PLoS One, 2016

^[4] Sautron E, Giustini C, Dang T, Moyet L, Salvi D, Crouzy S, Rolland N, Catty P and Seigneurin-Berny D. Identification of two conserved residues involved in copper release from chloroplast P_IB-1-ATPases. Journal of Biological Chemistry, 2016

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Keywords : ATPases-P1 | HMA6 | HMA8 | ChloroGenesis | metal homeostasis | copper | Transport and membrane proteins

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Cell & Plant Physiology Laboratory

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Copper pathway in the chloroplast

References

Keywords : ATPases-P1 | HMA6 | HMA8 | ChloroGenesis | metal homeostasis | copper | Transport and membrane proteins

On P1-type ATPases

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Cell & Plant Physiology Laboratory

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Chloroplast Proteome Dynamics and Biogenesis Team

Chromatin Dynamics and Developmental Transitions

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Floral Regulators: Function, structure and evolution

Biogenesis, dynamics and homeostasis of membrane lipids

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Analytical Platform of Lipidomics

In the same section :

Copper pathway in the chloroplast

References

Keywords : ATPases-P1 | HMA6 | HMA8 | ChloroGenesis | metal homeostasis | copper | Transport and membrane proteins

On P1-type ATPases

Browse the site

Alternative and Atomic Energies Agency

Browse the portal