​2025 :

Banerjee, S., Daetwyler, S., Bai, X., Michaud, M., Jouhet, J., Binns, D., Madhugiri, S., Johnson, E., Wang, C.-W., Fiolka, R., Toulmay, A., Prinz, W.A., 2025. The Vps13-like protein BLTP2 regulates phosphatidylethanolamine levels to maintain plasma membrane fluidity and breast cancer aggressiveness. Nat Cell Biol 27, 1125–1135. https://doi.org/10.1038/s41556-025-01672-3

Escuín, J.M., Claver, A., Luján, M.Á., Schilling, M., Jouhet, J., Savirón, M., López, M.V., Jarne, C., Alfonso, M., Cebolla, V.L., 2025. The valuable role of high-performance thin-layer chromatography in the lipidomic analysis of Thlaspi arvense, an emerging feedstock for biofuel production. JPC-J Planar Chromat 38, 455–465. https://doi.org/10.1007/s00764-025-00346-y

Le Moigne, D., Carletti, M., Amari, C., Bonnarde, R., Richard, F., Albrieux, C., Mahieu, M., Arrighi, M., Si-Larbi, G., Jouneau, P.-H., Gros, V., Louwagie, M., Roy, S., Gong, Y., Pan, Y., Hu, H., Bastien, O., Jouhet, J., Amato, A., Maréchal, E., Salvaing, J., 2025. Functional study of Phaeodactylum tricornutum Seipin highlights specificities of lipid droplets biogenesis in diatoms. New Phytologist 247, 2245–2269. https://doi.org/10.1111/nph.70350

Salomon, S., Schilling, M., Albrieux, C., Si Larbi, G., Jouneau, P.-H., Roy, S., Falconet, D., Michaud, M., Jouhet, J., 2025. Betaine lipids overproduced in seed plants are not imported into plastid membranes and promote endomembrane expansion. J Exp Bot 76, 980–996. https://doi.org/10.1093/jxb/erae458

Sérès, Y., Serbutoviez-Verville, C., Bonnarde, R., Schilling, M., Simon, M., Salvaing, J., Jouhet, J., Maréchal, E., Amato, A., 2025. Decoupling of plastid and endomembrane homeoviscous response to low temperature and darkness in Phaeodactylum tricornutum. BMC Plant Biol 25, 1436. https://doi.org/10.1186/s12870-025-07406-9

Yuan, Y., Iannetta, A.A., Kim, M., Sadecki, P.W., Arend, M., Tsichla, A., Águila Ruiz-Sola, M., Kepesidis, G., Falconet, D., Thevenon, E., Tardif, M., Brugière, S., Couté, Y., Kleman, J.P., Sizova, I., Schilling, M., Jouhet, J., Hegemann, P., Li-Beisson, Y., Nikoloski, Z., Bastien, O., Hicks, L.M., Petroutsos, D., 2025. Phototropin connects blue light perception to starch metabolism in green algae. Nat Commun 16, 2545. https://doi.org/10.1038/s41467-025-57809-3

2024 :

Baron, T., Jouhet, J., Schilling, M., Cussac, M., Charles, F., Vidal, V., Chervin, C., Sallanon, H., 2024. Postharvest lipidomics of lettuce leaves. Postharvest Biology and Technology 212, 112869. https://doi.org/10.1016/j.postharvbio.2024.112869

Claver, A., Luján, M.Á., Escuín, J.M., Schilling, M., Jouhet, J., Savirón, M., López, M.V., Picorel, R., Jarne, C., Cebolla, V.L., Alfonso, M., 2024. Transcriptomic and lipidomic analysis of the differential pathway contribution to the incorporation of erucic acid to triacylglycerol during Pennycress seed maturation. Front. Plant Sci. 15. https://doi.org/10.3389/fpls.2024.1386023

Coulon, D., Nacir, H., Bahammou, D., Jouhet, J., Bessoule, J.-J., Fouillen, L., Bréhélin, C., 2024. Roles of plastoglobules and lipid droplets in leaf neutral lipid accumulation during senescence and nitrogen deprivation. J Exp Bot 75, 6542–6562. https://doi.org/10.1093/jxb/erae301

Dorrell, R.G., Zhang, Y., Liang, Y., Gueguen, N., Nonoyama, T., Croteau, D., Penot-Raquin, M., Adiba, S., Bailleul, B., Gros, V., Pierella Karlusich, J.J., Zweig, N., Fernie, A.R., Jouhet, J., Maréchal, E., Bowler, C., 2024. Complementary environmental analysis and functional characterization of lower glycolysis-gluconeogenesis in the diatom plastid. Plant Cell 36, 3584–3610. https://doi.org/10.1093/plcell/koae168

Douchi, D., Si Larbi, G., Fel, B., Bonnanfant, M., Louwagie, M., Jouhet, J., Agnely, M., Pouget, S., Maréchal, E., 2024. Dryland Endolithic Chroococcidiopsis and Temperate Fresh Water Synechocystis Have Distinct Membrane Lipid and Photosynthesis Acclimation Strategies upon Desiccation and Temperature Increase. Plant Cell Physiol 65, 939–957. https://doi.org/10.1093/pcp/pcad139

Guéguen, N., Sérès, Y., Cicéron, F., Gros, V., Si Larbi, G., Falconet, D., Deragon, E., Gueye, S.D., Le Moigne, D., Schilling, M., Cussac, M., Petroutsos, D., Hu, H., Gong, Y., Michaud, M., Jouhet, J., Salvaing, J., Amato, A., Maréchal, E., 2024. Monogalactosyldiacylglycerol synthase isoforms play diverse roles inside and outside the diatom plastid. Plant Cell 36, 5023–5049. https://doi.org/10.1093/plcell/koae275

Jouhet, J., Alves, E., Boutté, Y., Darnet, S., Domergue, F., Durand, T., Fischer, P., Fouillen, L., Grube, M., Joubès, J., Kalnenieks, U., Kargul, J.M., Khozin-Goldberg, I., Leblanc, C., Letsiou, S., Lupette, J., Markov, G.V., Medina, I., Melo, T., Mojzeš, P., Momchilova, S., Mongrand, S., Moreira, A.S.P., Neves, B.B., Oger, C., Rey, F., Santaeufemia, S., Schaller, H., Schleyer, G., Tietel, Z., Zammit, G., Ziv, C., Domingues, R., 2024. Plant and algal lipidomes: Analysis, composition, and their societal significance. Progress in Lipid Research 96, 101290. https://doi.org/10.1016/j.plipres.2024.101290

Pan, Y., Zhang, W., Wang, X., Jouhet, J., Maréchal, E., Liu, J., Xia, X.-Q., Hu, H., 2024. Allele-dependent expression and functionality of lipid enzyme phospholipid:diacylglycerol acyltransferase affect diatom carbon storage and growth. Plant Physiol 194, 1024–1040. https://doi.org/10.1093/plphys/kiad581

You, L., Połońska, A., Jasieniecka-Gazarkiewicz, K., Richard, F., Jouhet, J., Maréchal, E., Banaś, A., Hu, H., Pan, Y., Hao, X., Jin, H., Allen, A.E., Amato, A., Gong, Y., 2024. Two plastidial lysophosphatidic acid acyltransferases differentially mediate the biosynthesis of membrane lipids and triacylglycerols in Phaeodactylum tricornutum. New Phytologist 241, 1543–1558. https://doi.org/10.1111/nph.19434

Zhu, J., Li, S., Chen, W., Xu, X., Wang, Xiaoping, Wang, Xinwei, Han, J., Jouhet, J., Amato, A., Maréchal, E., Hu, H., Allen, A.E., Gong, Y., Jiang, H., 2024. Delta-5 elongase knockout reduces docosahexaenoic acid and lipid synthesis and increases heat sensitivity in a diatom. Plant Physiol 196, 1356–1373. https://doi.org/10.1093/plphys/kiae297

2023 :

Ezzedine, J.A., Uwizeye, C., Si Larbi, G., Villain, G., Louwagie, M., Schilling, M., Hagenmuller, P., Gallet, B., Stewart, A., Petroutsos, D., Devime, F., Salze, P., Liger, L., Jouhet, J., Dumont, M., Ravanel, S., Amato, A., Valay, J.-G., Jouneau, P.-H., Falconet, D., Maréchal, E., 2023. Adaptive traits of cysts of the snow alga Sanguina nivaloides unveiled by 3D subcellular imaging. Nat Commun 14, 7500. https://doi.org/10.1038/s41467-023-43030-7

You, L., Jouhet, J., Maréchal, E., Amato, A., Hao, X., Zhang, D., Banaś, A., Gong, Y., 2023. Acyl-CoA:lysophosphatidylcholine acyltransferase from the unicellular diatom Phaeodactylum tricornutum (PtLPCAT1) is involved in triacylglycerol and galactoglycerolipid synthesis and enhances eicosapentaenoic acid accumulation in recombinant oleaginous yeast. Plant Biotechnology Journal 21, 238–240. https://doi.org/10.1111/pbi.13952

2022 :

Cheong, K.Y., Jouhet, J., Maréchal, E., Falkowski, P.G., 2022. The redox state of the plastoquinone (PQ) pool is connected to thylakoid lipid saturation in a marine diatom. Photosynth Res 153, 71–82. https://doi.org/10.1007/s11120-022-00914-x

Felix, J., Bumba, L., Liesche, C., Fraudeau, A., Rébeillé, F., El Khoury, J.Y., Huard, K., Gallet, B., Moriscot, C., Kleman, J.-P., Duhoo, Y., Jessop, M., Kandiah, E., Barras, F., Jouhet, J., Gutsche, I., 2022. The AAA+ ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane. Nat Commun 13, 5502. https://doi.org/10.1038/s41467-022-32992-9

Hao, X., Chen, W., Amato, A., Jouhet, J., Maréchal, E., Moog, D., Hu, H., Jin, H., You, L., Huang, F., Moosburner, M., Allen, A.E., Gong, Y., 2022. Multiplexed CRISPR/Cas9 editing of the long-chain acyl-CoA synthetase family in the diatom Phaeodactylum tricornutum reveals that mitochondrial ptACSL3 is involved in the synthesis of storage lipids. New Phytologist 233, 1797–1812. https://doi.org/10.1111/nph.17911

2021 :

Billey, E., Magneschi, L., Leterme, S., Bedhomme, M., Andres-Robin, A., Poulet, L., Michaud, M., Finazzi, G., Dumas, R., Crouzy, S., Laueffer, F., Fourage, L., Rébeillé, F., Amato, A., Collin, S., Jouhet, J., Maréchal, E., 2021. Characterization of the Bubblegum acyl-CoA synthetase of Microchloropsis gaditana. Plant Physiology 185, 815–835. https://doi.org/10.1093/plphys/kiaa110

Bo, D.D., Magneschi, L., Bedhomme, M., Billey, E., Deragon, E., Storti, M., Menneteau, M., Richard, C., Rak, C., Lapeyre, M., Lembrouk, M., Conte, M., Gros, V., Tourcier, G., Giustini, C., Falconet, D., Curien, G., Allorent, G., Petroutsos, D., Laeuffer, F., Fourage, L., Jouhet, J., Maréchal, E., Finazzi, G., Collin, S., 2021. Consequences of Mixotrophy on Cell Energetic Metabolism in Microchloropsis gaditana Revealed by Genetic Engineering and Metabolic Approaches. Frontiers in Plant Science 12.

Deragon, E., Schuler, M., Aiese Cigliano, R., Dellero, Y., Si Larbi, G., Falconet, D., Jouhet, J., Maréchal, E., Michaud, M., Amato, A., Rébeillé, F., 2021. An Oil Hyper-Accumulator Mutant Highlights Peroxisomal ATP Import as a Regulatory Step for Fatty Acid Metabolism in Aurantiochytrium limacinum. Cells 10, 2680. https://doi.org/10.3390/cells10102680

Lemel, L., Nieścierowicz, K., García-Fernández, M.D., Darré, L., Durroux, T., Busnelli, M., Pezet, M., Rébeillé, F., Jouhet, J., Mouillac, B., Domene, C., Chini, B., Cherezov, V., Moreau, C.J., 2021. The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules. J Lipid Res 62, 100059. https://doi.org/10.1016/j.jlr.2021.100059

Smith, R., Jouhet, J., Gandini, C., Nekrasov, V., Marechal, E., Napier, J.A., Sayanova, O., 2021. Plastidial acyl carrier protein Δ9-desaturase modulates eicosapentaenoic acid biosynthesis and triacylglycerol accumulation in Phaeodactylum tricornutum. The Plant Journal 106, 1247–1259. https://doi.org/10.1111/tpj.15231

2020 :

Berger, E., Colosetti, P., Jalabert, A., Meugnier, E., Wiklander, O.P.B., Jouhet, J., Errazurig-Cerda, E., Chanon, S., Gupta, D., Rautureau, G.J.P., Geloen, A., El-Andaloussi, S., Panthu, B., Rieusset, J., Rome, S., 2020. Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice. Molecular Therapy - Methods & Clinical Development 18, 880–892. https://doi.org/10.1016/j.omtm.2020.08.009

Breton, S., Jouhet, J., Guyet, U., Gros, V., Pittera, J., Demory, D., Partensky, F., Doré, H., Ratin, M., Maréchal, E., Nguyen, N.A., Garczarek, L., Six, C., 2020. Unveiling membrane thermoregulation strategies in marine picocyanobacteria. New Phytologist 225, 2396–2410. https://doi.org/10.1111/nph.16239

Degraeve-Guilbault, C., Gomez, R.E., Lemoigne, C., Pankansem, N., Morin, S., Tuphile, K., Joubès, J., Jouhet, J., Gronnier, J., Suzuki, I., Coulon, D., Domergue, F., Corellou, F., 2020. Plastidic Δ6 Fatty-Acid Desaturases with Distinctive Substrate Specificity Regulate the Pool of C18-PUFAs in the Ancestral Picoalga Ostreococcus tauri. Plant Physiol 184, 82–96. https://doi.org/10.1104/pp.20.00281

Jaussaud, A., Lupette, J., Salvaing, J., Jouhet, J., Bastien, O., Gromova, M., Maréchal, E., 2020. Stepwise Biogenesis of Subpopulations of Lipid Droplets in Nitrogen Starved Phaeodactylum tricornutum Cells. Frontiers in Plant Science 11.

Kumar Sharma, A., Mühlroth, A., Jouhet, J., Maréchal, E., Alipanah, L., Kissen, R., Brembu, T., Bones, A.M., Winge, P., 2020. The Myb-like transcription factor phosphorus starvation response (PtPSR) controls conditional P acquisition and remodelling in marine microalgae. New Phytologist 225, 2380–2395. https://doi.org/10.1111/nph.16248

Salvaing, J., Botella, C., Albrieux, C., Gros, V., Block, M.A., Jouhet, J., 2020. PUB11-Dependent Ubiquitination of the Phospholipid Flippase ALA10 Modifies ALA10 Localization and Affects the Pool of Linolenic Phosphatidylcholine. Front. Plant Sci. 11. https://doi.org/10.3389/fpls.2020.01070

2019 :

Calvez, P., Jouhet, J., Vié, V., Durmort, C., Zapun, A., 2019. Lipid Phases and Cell Geometry During the Cell Cycle of Streptococcus pneumoniae. Front. Microbiol. 10. https://doi.org/10.3389/fmicb.2019.00351

Chevalier, F., Cuyas, L., Jouhet, J., Gros, V., Chiarenza, S., Secco, D., Whelan, J., Seddiki, K., Block, M.A., Nussaume, L., Marechal, E., 2019. Interplay between Jasmonic Acid, Phosphate Signaling and the Regulation of Glycerolipid Homeostasis in Arabidopsis. Plant Cell Physiol 60, 1260–1273. https://doi.org/10.1093/pcp/pcz027

Chollet, C., Boutet-Mercey, S., Laboureur, L., Rincon, C., Méjean, M., Jouhet, J., Fenaille, F., Colsch, B., Touboul, D., 2019. Supercritical fluid chromatography coupled to mass spectrometry for lipidomics. Journal of Mass Spectrometry 54, 791–801. https://doi.org/10.1002/jms.4445

Decelle, J., Stryhanyuk, H., Gallet, B., Veronesi, G., Schmidt, M., Balzano, S., Marro, S., Uwizeye, C., Jouneau, P.-H., Lupette, J., Jouhet, J., Maréchal, E., Schwab, Y., Schieber, N.L., Tucoulou, R., Richnow, H., Finazzi, G., Musat, N., 2019. Algal Remodeling in a Ubiquitous Planktonic Photosymbiosis. Current Biology 29, 968-978.e4. https://doi.org/10.1016/j.cub.2019.01.073