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We use biochemical and structural analysis to characterize the properties of this interesting protein from various plants. In collaboration with the lab. of Dr. C. Müller, we have solved the crystallographic structure of Arabidopsis LFY DNA binding domain in complex with its cognate DNA. This work revealed that LFY possesses an Helix-Turn-Helix motif buried in a unique seven-helix fold that contacts DNA over a large region (19 pb).
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.