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LFY DNA binding

Published on 14 January 2019

VideoLEAFY_dimer.flv

We use biochemical and structural analysis to characterize the properties of this interesting protein from various plants. In collaboration with the lab. of Dr. C. Müller, we have solved the crystallographic structure of Arabidopsis LFY DNA binding domain in complex with its cognate DNA. This work revealed that LFY possesses an Helix-Turn-Helix motif buried in a unique seven-helix fold that contacts DNA over a large region (19 pb).​​


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